Symposium Louis-Jeantet 2017

10 octobre 2017 08:50 - 17:30
Centre Médical Universitaire (CMU), Genève

Durant ce Symposium, les organisateurs et des chercheurs actifs dans le même domaine feront le point sur l’avancement de leurs travaux et dresseront l’état des lieux des domaines concernés.

Télécharger le programme (PDF)

Pour plus d'informations, veuillez contacter:
Costanza Panbianco
Coordination Symposium
T: +41 22 704 36 42
F: +41 22 704 36 37
panbianco@jeantet.ch

Fondation Louis-Jeantet
Chemin Rieu 17
1208 Genève
Suisse
T: +41 22 704 36 36
F: +41 22 704 36 37
info@jeantet.ch

 

THE GENETIC EVOLUTION OF CANCER

Tuesday, October 10 2017
Centre Médical Universitaire (CMU), Geneva - Auditorium A250

08:15 – 08:50
Registration and welcome coffee
08:50 – 09:00
Dominique Soldati-Favre
Vice-Dean of the Faculty of Medicine, University of Geneva
Opening

Session 1: The genetic evolution of cancer I

Session 1.1: 09:00 – 10:30

Chairperson:
Stephen West (web link)
2007 Louis-Jeantet prize-winner
The Francis Crick Institute, London
Co-chairperson:
Patrick Meraldi
Faculty of Medicine, University of Geneva
09:00 – 09:30
Ketan Patel
MRC Laboratory of Molecular Biology, Cambridge
Alcohol, Metabolism and Endogenous DNA damage
09:30 – 10:00
Stephen West (web link)
The Francis Crick Institute, London
Unresolved recombination intermediates as a source of DNA breaks and chromosome aberrations
10:00 – 10:30
Titia de Lange
Rockefeller University, New York
Telomeres and genome instability in cancer
10:30 – 11:00
Break

Session 1.2: 11:00 – 12:30

11:00 – 11:30
Thanos Halazonetis
University of Geneva, Geneva
Mechanisms of oncogene-induced DNA replication stress
11:30 – 12:00
Jos Jonkers
Netherlands Cancer Institute, Amsterdam
Genetic dissection of tumor development, therapy response and resistance in mouse models of BRCA-deficient breast cancer
12:00 – 12:30
Jiri Lukas
Novo Nordisk Foundation Center for Protein Research,Copenhagen
Confinement, heritability and intrinsic limitations of cellular responses to DNA replication stress
12:30 – 13:45
Lunch

Session 2: The genetic evolution of cancer II

Session 2.1: 13:45 – 15:15

Chairperson
Mike Stratton (web link)
2013 Louis-Jeantet prize-winner
Wellcome Trust Sanger Institute, Cambridge
Co-Chairperson
Ariel Ruiz i Altaba
Faculty of Medicine, University of Geneva
13:45 – 14:15
Núria López-Bigas
Institute for Research in Biomedicine, Barcelona
Coding and non-coding cancer mutations
14:15 – 14:45
Charles Swanton
The Francis Crick Institute and UCL Hospitals, London
Chromosomal order and chaos in lung cancer evolution and immune surveillance
14:45 – 15:15
Mike Stratton (web link)
Wellcome Trust Sanger Institute, Cambridge
Signatures of Mutational Processes
15:15 – 15:45
Break

Session 2.2: 15:45 – 17:15

15:45 – 16:15
Ian Tomlinson
Institute of Cancer and Genomic Sciences, Birmingham
Mutational and selective constraints on cancer evolution
16:15 – 16:45
Hans Clevers
Hubrecht Institute, Utrecht
Lgr5 Stem Cell-based Organoids in human disease
16:45 – 17:15
Stylianos Antonarakis
University of Geneva, Geneva
Somatic mutation rate
17:15 – 17:25
Stephen West and Mike Stratton
Concluding remarks
17:25
End of the Symposium

Télécharger le programme (PDF)

Pour plus d'informations, veuillez contacter:
Costanza Panbianco
Coordination Symposium
T: +41 22 704 36 42
F: +41 22 704 36 37
panbianco@jeantet.ch

Fondation Louis-Jeantet
Chemin Rieu 17
1208 Genève
Suisse
T: +41 22 704 36 36
F: +41 22 704 36 37
info@jeantet.ch